Lipids are the main integral component of cellular membranes. Membrane lipids are heterogeneous, and their distribution and variety changes across different organisms, cell types, organelles, membrane layers, bilayer-leaflets, and membrane subdomains. An abnormal distribution of cellular lipids is associated with numerous diseases, including cancer, cardiovascular and neurodegenerative disease.

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Our goal is to unveil previously unrecognized mechanisms of lipid transport, understand how they are regulated by nutritional cues, and how the disruption of these pathways contributes to the onset of lipid-related disorders.